Future therapies to help people live healthy lives for longer could be developed from drugs that release tiny amounts of the gas hydrogen sulfide (H2S), new research has indicated. It is announced in summary of article published in PNAS(10.1073/pnas.2216141120 ).
A study from the University of Exeter, funded by the US Army and charity The United Mitochondrial Disease Foundation, found that targeting tiny amounts of H2S to specific areas of cells in adult worms using a H2S-releasing molecule called AP39, greatly improved health and activity as they aged. The research, published in PNAS concludes that targeting H2S specifically to the energy-generating machinery of cells (mitochondria) could one day be used as a healthy aging therapeutic.
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